Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease. Certain clinical forms of the disease may cause significant discomfort and negatively impact patients’ quality of life. The first-line treatment is topical corticosteroids. The purpose of this narrative review is to evaluate the influence of corticosteroid injections in the treatment of OLP. Methods: A search of the literature was conducted in October 2025 using the following databases: PubMed, Web of Science, Scopus, and Cochrane. Results: Fifteen studies were evaluated. Injections with triamcinolone acetonide at a concentration of 10–40 mg/mL at weekly intervals demonstrated efficacy in reducing pain and healing OLP lesions in these studies. They showed minor adverse effects. Conclusions: Noting the limitations of this narrative review, intralesional corticosteroid injections are an effective and safe method of treating OLP. They should be considered in patients with symptomatic OLP.
Miazga-Rychlik et al. (Fri,) studied this question.
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