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This research aims to evaluate the effectiveness of blood culture stewardship in reducing CLABSIs.

P-823. Blood Culture Stewardship: An Essential Practice for CLABSI Reduction

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This research aims to evaluate the effectiveness of blood culture stewardship in reducing CLABSIs.
Developed a blood culture collection kit and provided stewardship education on bacteremia risk.
Added pre-test probability of bacteremia guidance to computerized provider order entry for blood cultures.
Monitored monthly blood culture orders and CLABSI rates before and after interventions.
Blood culture orders decreased from 2896 to 1909 monthly, a 35% reduction.
True bacteremia rates remained stable at 20% before and 23% after the intervention.
CLABSI occurrences decreased from 8 to 2, achieving a 75% reduction.

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Interventions improved blood culture quality in a health system, reducing CLABSI rates by 75% after education and guidance.

Besandre et al. (2026) studied this question.

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