Disparities in pancreatic cancer burden across states, sex, and risk factors: A GBD 2021 study.

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This research aims to identify and analyze disparities in pancreatic cancer burden across different states, sexes, and risk factors.
Data sourced from the Institute for Health Metrics and Evaluation Global Burden of Disease 2021 Results Tool.
Analyzed age-standardized death and DALY rates by state and sex.
Conducted age-stratified crude mortality and DALY assessments for high-burden groups.
Utilized descriptive statistics for data interpretation.
Louisiana and Mississippi ranked highest in pancreatic cancer incidence, mortality, and DALY rates.
Males showed higher rates compared to females, with sharp increases after age 65.
Southern and Midwestern states exhibited the greatest burden.
Smoking and high body mass index were significant risk factors for DALYs.
Peak prevalence was noted in older adults, particularly those aged 80 and above.

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Analysis reveals high pancreatic cancer incidence and mortality in southern states, suggesting resource allocation improvements for older adults.

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Adusumilli et al. (2026) studied this question.

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