What type of study is this?

This is a Cohort Study study (also classified as: Human Clinical Trial).

What question did this study set out to answer?

To evaluate the impact of timely antivenom administration on neurotoxic outcomes in cobra envenoming cases.

January 14, 2026BiomedicinesOpen Access

Early Clinical Approach Prevents Severe Neurotoxicity Following Cobra Envenoming: An Integrated Experimental and Multi-Center Clinical Study in Thailand

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Authors

SLSethapong LertsakulbunluePhramongkutklao Hospital MCMusleeha ChesorPrincess of Naradhiwas University PPPanuwat PromsornPrincess of Naradhiwas University

Discussion

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Implication

Retrospective study found early antivenom reduces neurotoxicity and respiratory failure in cobra envenomed patients, highlighting clinical significance.

Key Points

To evaluate the impact of timely antivenom administration on neurotoxic outcomes in cobra envenoming cases.
Retrospective analysis of 69 cobra envenoming cases in Thailand.
Histopathological examination of the diaphragm in experimentally envenomed rats.
Assessment of delayed hospital arrival effects on neurotoxic outcomes.
Delayed hospital arrival beyond one hour linked to severe neurotoxicity.
Adverse reactions occurred in 39.1% of antivenom cases.
Histopathological changes in the diaphragm observed within 1 hour of envenomation.

Cite This Study

Lertsakulbunlue et al. (2026) studied this question.

synapsesocial.com/papers/6966f2e313bf7a6f02c0027f https://doi.org/10.3390/biomedicines14010144

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Implication

Retrospective study found early antivenom reduces neurotoxicity and respiratory failure in cobra envenomed patients, highlighting clinical significance.

Early Clinical Approach Prevents Severe Neurotoxicity Following Cobra Envenoming: An Integrated Experimental and Multi-Center Clinical Study in Thailand

Discussion

Member takes

Implication

Key Points

Cite This Study

Early Clinical Approach Prevents Severe Neurotoxicity Following Cobra Envenoming: An Integrated Experimental and Multi-Center Clinical Study in Thailand

Discussion

Member takes

Implication

Key Points

Cite This Study

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