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Research demonstrates a liquid biopsy approach predicts pancreatic cancer in high-risk people, suggesting better monitoring of this aggressive disease.
Summary: Pancreatic cancer is known as the “king of cancers” due to its aggressive progression and poor prognosis. Wang, Wang, Zhang, and colleagues develop a promising liquid biopsy approach that uses features derived from a single run of low-pass whole-genome cell-free DNA sequencing to predict pancreatic cancer years before diagnosis in a large asymptomatic high-risk cohort, markedly outperforming existing biomarkers and projecting survival gains. See related article by Wang et al., p. 66
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Tsui et al. (2026) studied this question.
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