Medical image segmentation acts as a foundational element of medical image analysis. Yet its accuracy is frequently limited by the scale fluctuations of anatomical targets and the intricate contextual traits inherent in medical images—including vaguely defined structural boundaries and irregular shape distributions. To tackle these constraints, we design a multi-scale feature attention network (MFA-Net), customized specifically for thyroid nodule, skin lesion, and breast lesion segmentation tasks. This network framework integrates three core components: a Bidirectional Feature Pyramid Network (Bi-FPN), a Slim-neck structure, and the Convolutional Block Attention Module (CBAM). CBAM steers the model to prioritize boundary regions while filtering out irrelevant information, which in turn enhances segmentation precision. Bi-FPN facilitates more robust fusion of multi-scale features via iterative integration of top-down and bottom-up feature maps, supported by lateral and vertical connection pathways. The Slim-neck design is constructed to simplify the network’s architecture while effectively merging multi-scale representations of both target and background areas, thus enhancing the model’s overall performance. Validation across four public datasets covering thyroid ultrasound (TNUI-2021, TN-SCUI 2020), dermoscopy (ISIC 2016), and breast ultrasound (BUSI) shows that our method outperforms state-of-the-art segmentation approaches, achieving Dice similarity coefficients of 0.955, 0.971, 0.976, and 0.846, respectively. Additionally, the model maintains a compact parameter count of just 3.05 million and delivers an extremely fast inference latency of 1.9 milliseconds—metrics that significantly outperform those of current leading segmentation techniques. In summary, the proposed framework demonstrates strong performance in thyroid, skin, and breast lesion segmentation, delivering an optimal trade-off between high accuracy and computational efficiency.
Zhao et al. (Mon,) studied this question.