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January 14, 2026Open Forum Infectious DiseasesOpen Access

P-491. Optimizing Delivery of HIV Pre-Exposure Prophylaxis (PrEP) to Adolescents at Risk of HIV Infection

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Authors

CFCharlotte FormellerWEWendi EhrmanMTMargaret Thew

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Overview

Quality improvement project increased HIV pre-exposure prophylaxis prescribing among adolescents, indicating effective interventions address barriers.

Key Points

  • Identify barriers to prescribing HIV pre-exposure prophylaxis among pediatric providers and evaluate targeted interventions.
  • Surveyed pediatric primary care providers regarding PrEP prescribing barriers.
  • Implemented educational sessions, added injectable PrEP to formulary, and utilized EMR tools.
  • Monitored PrEP initiation rates among adolescents at risk using Plan-Do-Study-Act cycles.
  • 93% of surveyed PCPs had never prescribed PrEP; 51% lack awareness of its indications.
  • Prescribing comfort increased from 36% to 100% post-educational session for 63% of PCPs.
  • HIV PrEP prescribing rates rose from 0.6% to 3.8% post-intervention.

Cite This Study

Formeller et al. (2026) studied this question.

synapsesocial.com/papers/6966f31513bf7a6f02c00a48https://doi.org/10.1093/ofid/ofaf695.706
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P-312. Improving Utilization of PrEP Across Internal Medicine Resident Clinics2026
  2. 2P-496. Adolescent Provider Perspectives on Sexual Health Screening and Preventive Care2026
  3. 3Developing an HIV Pre-Exposure Prophylaxis Toolkit for Adolescent and Young Adults: Serving Primary Care Providers to Support Future Implementation Using the Consolidated Framework for Implementation Research2026
  4. 4P-289. Assessing Knowledge of HIV Pre-exposure Prophylaxis before and after Resident Education2026
  5. 5P-292. Impact of Emergency Department Pharmacist-Led HIV Pre-Exposure Prophylaxis Initiation in Patients with Positive Sexually Transmitted Infection Testing2026