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January 14, 2026Open Forum Infectious DiseasesOpen Access

P-1432. Communicating Readiness: Lessons Learned and Key Takeaways from an Ebola Vaccine Rollout at a Regional Emerging Special Pathogens Treatment Center

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Authors

ABArianna I. BosharaDenver Health Medical CenterJWJacob WierschDenver Health Medical CenterMFMaria G. FrankDenver Health Medical Center

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Implication

Pilot efforts to enhance vaccine education improved communication among healthcare workers, indicating better logistics are needed.

Key Points

  • To assess operational readiness and identify barriers to Ebola vaccine uptake among healthcare workers.
  • Conducted a focused rollout of the rVSV-ZEBOV vaccine for eligible healthcare workers.
  • Implemented a coordinated process involving infection prevention, pharmacy, and outpatient operations.
  • Collected observational feedback through team debriefs and informal reports.
  • Only 9 out of 30 interested healthcare worker members were vaccinated, highlighting communication gaps.
  • Clinic and pharmacy operations were well-coordinated despite scheduling challenges.
  • Misinformation about the vaccine's nature contributed to hesitancy among staff.

Cite This Study

Boshara et al. (2026) studied this question.

synapsesocial.com/papers/6966f33213bf7a6f02c01128https://doi.org/10.1093/ofid/ofaf695.1619
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Knowledge, attitudes, and practices and long-term immune response after rVSVΔG-ZEBOV-GP Ebola vaccination in healthcare workers in high-risk districts in Uganda2024 · 7 citations
  2. 2EBOLA VIRUS VACCINES AND RECENT ADVANCEMENTS: A SCOPING REVIEW2026
  3. 3EBOLA VIRUS VACCINES AND RECENT ADVANCEMENTS: A SCOPING REVIEW2026
  4. 4Effectiveness of rVSV-ZEBOV vaccination during the 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo: a retrospective test-negative study2024 · 55 citations
  5. 5Use of Ebola Vaccines — Worldwide, 2021–20232024 · 28 citations