What question did this study set out to answer?

This review aims to examine the effects of pulsed radiofrequency on the immunological system and its implications for chronic pain management.

January 14, 2026Exploration of ImmunologyOpen Access

Role of pulsed radiofrequency on the immunological system in chronic pain patients: a narrative review

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Authors

LOLeonardo Ona JMJacopo MoscaPoliclinico Umberto I MLMatteo Luigi Giuseppe LeoniUniversità degli studi di Cassino e del Lazio Meridionale

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Implication

Narrative review highlights pulsed radiofrequency's potential in managing pain and regulating inflammation, indicating improvements in neuropathic and musculoskeletal pain.

Key Points

This review aims to examine the effects of pulsed radiofrequency on the immunological system and its implications for chronic pain management.
Narrative review of existing literature on pulsed radiofrequency and its effects on pain and the immune system.
Analysis of clinical studies, including randomized controlled trials and observational studies.
Discussion of techniques and mechanisms of action related to pulsed radiofrequency.
Evaluation of challenges and recommendations for future research.
Pulsed radiofrequency shows promise in regulating inflammatory processes and managing neuropathic and musculoskeletal pain.
Evidence from randomized controlled trials suggests effectiveness, though many studies lack methodological quality.
Observational studies indicate potential benefits in chronic inflammatory and degenerative diseases.

Cite This Study

Ona et al. (2026) studied this question.

synapsesocial.com/papers/6966f33213bf7a6f02c01194 https://doi.org/10.37349/ei.2026.1003235

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Implication

Narrative review highlights pulsed radiofrequency's potential in managing pain and regulating inflammation, indicating improvements in neuropathic and musculoskeletal pain.

Role of pulsed radiofrequency on the immunological system in chronic pain patients: a narrative review

Discussion

Member takes

Implication

Key Points

Cite This Study

Role of pulsed radiofrequency on the immunological system in chronic pain patients: a narrative review

Discussion

Member takes

Implication

Key Points

Cite This Study

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