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January 14, 2026Food and Bioprocess Technology3 citations

Supercritical CO2 Coprocessing of Agricultural Materials for the Extraction of Bioactives

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FDFrancisco Díaz-SeoaneSISheyma InoubliBDBeatriz Díaz-Reinoso

Key Points

  • This review explores the coextraction of bioactives and cosolvents from agricultural materials using supercritical CO2 extraction.
  • Overview of coextraction techniques
  • Discussion on the use of vegetal oil as a cosolvent
  • Evaluation of environmental advantages of scCO2 extraction
  • Coextraction provides a solvent-free method for bioactive extraction
  • Utilization of agricultural wastes can lead to novel and stable formulations
  • Improved bioavailability of extracted bioactives for food and nutraceutical products

Abstract

Supercritical carbon dioxide (scCO 2 ) extraction offers environmental advantages over other techniques for extracting bioactive compounds from plant biomass. The effectiveness of scCO 2 extraction can be enhanced by including a cosolvent in the process. When a vegetal oil is used as a cosolvent, further separation stages would be avoided, and a final product with improved functional and biological properties for food and nutraceutical products can be obtained. Coextraction or the joint extraction of bioactives from a primary solid matrix and an oil, acting as a cosolvent, from a secondary matrix, has been proposed as a solvent-free approach. This review presents an overview on the potential of coextraction as a strategy to valorize food and agricultural wastes and to develop novel products, containing both the solute and the cosolvent in a valuable, more stable, and bioavailable formulation of the bioactives.

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Cite This Study

Díaz-Seoane et al. (2026) studied this question.

synapsesocial.com/papers/6966f5183603a7c209c0e2a1https://doi.org/10.1007/s11947-025-04179-9
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