Lower heart rate at 12, 24, and 48 hours post-EVT is independently associated with better outcomes in large vessel occlusion stroke patients, especially in posterior circulation cases.
Does resting heart rate post-endovascular treatment predict functional outcomes in patients with anterior versus posterior circulation large vessel occlusion acute ischemic stroke?
Lower resting heart rate following successful endovascular treatment for large vessel occlusion stroke independently predicts better 3-month functional outcomes, particularly in posterior circulation strokes.
Absolute Event Rate: 0% vs 0%
Background: The prognostic significance of resting heart rate (HR) in acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) after endovascular treatment (EVT) remains to be elucidated. Objectives: To determine whether HR is differentially associated with functional outcomes in patients dichotomized by anterior (ACS) or posterior circulation stroke (PCS) after successful reperfusion. Design: A multicenter retrospective cohort study. Methods: We retrospectively analyzed consecutive successfully recanalized LVO-AIS patients with complete HR recordings at admission, 30 min, 12 h, 24 h, and 48 h post-EVT. A good outcome was defined as modified Rankin Scale (mRS) 0–2 for ACS or mRS 0–3 for PCS at 3 months. Binary logistic regression and receiver operating characteristic analyses were used to assess associations and predictive performance. Results: Among 505 patients (362 ACS, 143 PCS), lower HR at 12, 24, and 48 h post-EVT was independently associated with good outcomes in both groups. HR showed higher predictive accuracy for PCS (AUC: 0.872–0.885) than for ACS (AUC: 0.732–0.762). Conclusion: HR following EVT independently predicts functional outcome in LVO patients, demonstrating stronger predictive value for PCS than ACS. These results highlight the potential of HR monitoring in post-EVT management.
Zhang et al. (Thu,) reported a other. Lower heart rate at 12, 24, and 48 hours post-EVT is independently associated with better outcomes in large vessel occlusion stroke patients, especially in posterior circulation cases.