CTSB-positive tumor-associated macrophages shape prognosis and therapeutic response in lung adenocarcinoma

Key Points

• The study aims to assess how ctsb-positive tumor-associated macrophages influence prognosis and therapeutic responses in lung adenocarcinoma.
• Development of a clinical prediction model (CTRS)
• Evaluation of patient clinical outcomes
• Analysis of tumor-associated macrophage characteristics
• Identified ctsb-positive macrophages as significant predictors of patient outcomes
• Demonstrated a relationship between macrophage presence and therapeutic response
• Showed potential utility of CTRS in guiding clinical decision-making