Why the study?
Does beta blocker therapy reduce all cause mortality and reinfarction in patients with acute or past myocardial infarction?
Meta-Analysis (n=54,234)
null
randomized
Yes
Does beta blocker therapy reduce all cause mortality and reinfarction in patients with acute or past myocardial infarction?
Long-term beta-blocker therapy significantly reduces all-cause mortality and non-fatal reinfarction in patients after myocardial infarction, whereas short-term acute use does not show a significant mortality benefit.
beta Blockers are effective in long term secondary prevention after myocardial infarction, but they are underused in such cases and lead to avoidable mortality and morbidity.
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Freemantle et al. (1999) conducted a meta-analysis in myocardial infarction (n=54,234). â blockers vs. control was evaluated on all cause mortality (OR 0.77, 95% CI 0.69-0.85, p=<0.001).
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