â blockers reduced all cause mortality by 23% in long term trials compared to control with an odds ratio of 0.77 (95% CI 0.69 to 0.85).
Meta-Analysis (n=54,234)
null
randomized
Yes
Does beta blocker therapy reduce all cause mortality and reinfarction in patients with acute or past myocardial infarction?
Long-term beta-blocker therapy significantly reduces all-cause mortality and non-fatal reinfarction in patients after myocardial infarction, whereas short-term acute use does not show a significant mortality benefit.
Effect estimate: OR 0.77 (95% CI 0.69-0.85)
p-value: p=<0.001
beta Blockers are effective in long term secondary prevention after myocardial infarction, but they are underused in such cases and lead to avoidable mortality and morbidity.
Freemantle et al. (1999) conducted a meta-analysis in myocardial infarction (n=54,234). â blockers vs. control was evaluated on all cause mortality (OR 0.77, 95% CI 0.69-0.85, p=<0.001). â blockers reduced all cause mortality by 23% in long term trials compared to control with an odds ratio of 0.77 (95% CI 0.69 to 0.85).