Premenopausal status protects breast cancer survivors from TAC-induced vascular dysfunction, likely due to estrogen-mediated protection against oxidative stress and eNOS inhibition.
Is menopausal status associated with docetaxel-induced vascular dysfunction in breast cancer patients?
Premenopausal status appears to protect breast cancer survivors from docetaxel-induced vascular dysfunction, likely via estrogen-mediated mechanisms.
Absolute Event Rate: 0% vs 0%
TAC-induced vascular dysfunction seen in breast cancer survivors is absent in premenopausal women, likely owing to estrogen-mediated protection against oxidative stress and eNOS inhibition.
Szczepaniak et al. (Thu,) reported a other. Premenopausal status protects breast cancer survivors from TAC-induced vascular dysfunction, likely due to estrogen-mediated protection against oxidative stress and eNOS inhibition.
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