ABSTRACT Iron(II) triflate, Fe(OTf) 2 (OTf = CF 3 SO 3 − ) has been used as a catalyst for directing group‐free intermolecular C(sp 3 )─H fluorination in the absence of any added ligand. This transformation proceeds under mild conditions with low catalyst loading utilizing Selectfluor as the fluorine source. Reaction conditions were optimized, a range of substrates were evaluated, and the functional group tolerance of the fluorination strategy was systematically investigated. A plausible catalytic cycle is proposed based on the results of control experiments.
Dilinaer et al. (Thu,) studied this question.