A Simulation Procedure for Stereological Correction of Early AMD Lesion Sizes Observed in Single OCT-B-Scans

Key Points

• The aim is to improve the accuracy of AMD classifications through stereological correction of lesion sizes derived from OCT data.
• Developed a simulation procedure for stereological correction.
• Applied corrections to sizes of early AMD lesions observed in OCT scans.
• Reexamined categorial AMD classifications based on corrected data.
• Demonstrated that stereological correction significantly altered lesion size measurements.
• Indicated potential discrepancies in AMD classifications when not corrected.