The effect of astragaloside IV on a model of isoproterenol-induced hypertrophic injury in H9c2 cells

Key Points

• The aim is to investigate how astragaloside IV affects hypertrophic injury induced by isoproterenol in H9c2 cells.
• Utilized H9c2 cell line as a model for heart injury
• Induced hypertrophy using isoproterenol
• Administered various concentrations of astragaloside IV
• Assessed cell viability and hypertrophic markers
• Astragaloside IV significantly reduced cell injury caused by isoproterenol
• Lower levels of hypertrophic markers were observed with treatment
• Increased cell viability compared to untreated controls