Abstract Objective To investigate demographic differences in COVID-19 vaccination uptake and assess whether vaccination status is associated with societal participation, mental health, and quality of life among individuals with complicated mild to severe traumatic brain injury (TBI). Design Secondary analysis of a prospective, longitudinal cohort study using the TBI Model Systems (TBIMS) National Database from 1,961 individuals aged 16-years-old and older who completed interviews between October 1, 2021, and January 15, 2023, and responded to questions regarding COVID-19 vaccination status. Demographic, injury severity, societal participation, mental health, and quality of life metrics were compared between those with and without COVID-19 vaccination. Results Vaccinated individuals (68%) were more likely to be older, female, non-smokers, White, and of Asian American or Hispanic ethnicity. TBI severity did not significantly differ between vaccinated and unvaccinated groups. In multivariate analysis, vaccination status was not independently associated with social participation (PART-O), anxiety (GAD-7), depression (PHQ-9), or quality of life (SWLS). Conclusion Demographic disparities in vaccination uptake exist among individuals with TBI, but vaccination status was not independently linked to mental health, participation, or quality of life outcomes. These findings underscore the need for targeted outreach to address vaccination gaps and promote health equity in this vulnerable population.
Chen et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: