Retrospective study identifies NLR, PLR, and SII as potential markers to differentiate PV from secondary polycythemia, suggesting improved diagnostic approaches.
Key Points
This study aims to evaluate the effectiveness of inflammatory markers in distinguishing polycythemia vera from secondary polycythemia.
Conducted a retrospective analysis of clinical and laboratory data from 281 patients.
Included 110 patients with polycythemia vera and 181 with secondary polycythemia.
Utilized metrics such as NLR, PLR, and SII to compare groups.
Established diagnosis based on World Health Organization criteria.
Median NLR, PLR, and SII significantly higher in PV group compared to SP group (p < 0.001).
NLR, PLR, SII showed sensitivities and specificities over 85%.
Area under the curve for these tests greater than 0.9, indicating high diagnostic effectiveness.