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January 17, 2026Brain SciencesOpen Access

Relationships Among Functional Status, Global Self-Reported Categorical Measure of Activity Level, Health-Related Quality of Life and Psychological State in Patients with Parkinson’s Disease in Greece

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Authors

ACAnna ChristakouNKNektaria Angeliki KomisopoulouALAmalia Panagiota Louka

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Overview

Study examines relationships between activity level, quality of life, and psychological state in Parkinson’s patients, indicating complex interconnections.

Key Points

  • This research aims to explore how functional status, activity level, health-related quality of life, and psychological state relate in Parkinson's disease patients.
  • Participants completed the Parkinson’s Disease Questionnaire for HRQoL assessment.
  • Participants used the Hospital Anxiety and Depression Scale (HADS) for psychological state evaluation.
  • Functional status was evaluated through the Five Times Sit to Stand Test (FTSST) and the Berg Balance Scale (BBS).
  • Spearman correlation analysis and linear regression models were employed to analyze data.
  • Participants reported high anxiety (mean = 9.67) and depressive symptoms (mean = 8.97).
  • Functional status had a strong negative correlation with HRQoL (r = -0.696).
  • Depression was positively linked with poorer HRQoL (r = 0.618) and negatively with activity levels (r = -0.545).
  • Significant predictors of HRQoL included balance, disease duration, anxiety, and lower limb function.

Cite This Study

Christakou et al. (2026) studied this question.

synapsesocial.com/papers/696b2696d2a12237a9349ce3https://doi.org/10.3390/brainsci16010090
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of worrier trait with the risk of Parkinson's disease: a longitudinal study based on 457,180 UK Biobank participants2025 · 1 citations
  2. 2Effect of Physical Activity on Depression in Patients with Parkinson’s Disease: A Systematic Review and Meta-Analysis2022 · 25 citations