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The aim is to explore urinary metabolite differences between foundry workers and surrounding residents to assess occupational exposure effects.

January 17, 2026Journal of XenobioticsOpen Access

Urinary Metabolomics as a Window into Occupational Exposure: The Case of Foundry Workers

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The aim is to explore urinary metabolite differences between foundry workers and surrounding residents to assess occupational exposure effects.
Investigated urinary metabolic profiles from 64 foundry workers and 78 residents.
Utilized multivariate statistical modeling for data analysis.
Compared metabolic patterns and associated demographics between both groups.
Foundry workers had lower levels of several amino acids (e.g., valine, alanine).
Higher levels of branched-chain amino acid catabolites were found in workers.
Variations in gut microbiota-related metabolites were detected, including phenylacetylglycine.

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Multivariate analysis reveals distinct urinary metabolite patterns in foundry workers, indicating health impacts of exposure.

Rosa et al. (2026) studied this question.

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