EDTA-Mediated Crosslinking of Guar gum: A Sustainable Platform for Transdermal Curcumin Delivery

Key Points

• The research aims to develop a sustainable method for curcumin delivery through EDTA-mediated crosslinking of guar gum.
• Crosslinking guar galactomannan with EDTA to create a polymeric matrix.
• Characterization of the crosslinked polymer for stability and delivery efficiency.
• Evaluation of transdermal delivery potential of curcumin using the polymer.
• Improved stability of the guar gum matrix upon crosslinking with EDTA.
• Enhanced release rates of curcumin from the crosslinked guar gum compared to non-crosslinked alternatives.
• Demonstrated effectiveness in transdermal applications, highlighting potential in biomedical fields.