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January 18, 2026Chemical Science0 citationsOpen Access

Enantioselective C-H Functionalization: Logic and Applications in the Total Synthesis of Natural Products

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PQPu‐Fan QianBSBing-Feng Shi

Key Points

  • The research aims to explore the role of enantioselective C–H functionalization in the synthesis of natural products.
  • Analyzed various enantioselective C-H functionalization techniques
  • Examined structural diversity of natural products
  • Explored applications in drug discovery and biomaterial development
  • Successful demonstration of enantioselective C-H functionalization in synthetic pathways
  • Increased efficiency in synthesizing diverse natural products
  • Highlighted significant bioactivities related to synthesized products

Abstract

Natural products, with their profound structural diversity and potent bioactivities, represent an invaluable source of inspiration for drug discovery and biomaterial development. The integration of enantioselective C–H functionalization into synthetic...

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Cite This Study

Qian et al. (2026) studied this question.

synapsesocial.com/papers/696c772aeb60fb80d1395659https://doi.org/10.1039/d5sc08653a
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