Review discusses C–H functionalization techniques in natural product synthesis, highlighting their role in retrosynthesis.
In this review, recent examples featuring C-H functionalization in the synthesis of complex natural products are discussed. A focus is given to the way in which C-H functionalization can influence the logical process of retrosynthesis, and the review is organized by the type and method of C-H functionalization.
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Abrams et al. (2018) studied this question.
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