Construction of Sulfur-substituted Methylenecyclobutanes via Thioaromatization of 1.1.1Propellane with Sulfenamides †

Key Points

• This research aims to develop a new method for synthesizing sulfur-substituted methylenecyclobutanes.
• Utilized a metal-free catalytic approach for synthesis
• Applied thioaromatization process on [1.1.1]propellane
• Demonstrated transformation with minimal byproducts
• Achieved high atom economy in the synthesis process
• Successfully generated a range of sulfur-substituted methylenecyclobutanes
• Demonstrated broad functional group tolerance