Multinational survey reveals 62.3% tetracycline resistance in Neisseria gonorrhoeae, suggesting urgent action is needed.
In 2024, based on the European Committee on Antimicrobial Susceptibility Testing breakpoint, we observed a tetracycline resistance prevalence of 62.3% (2,231/3,579) in Neisseria gonorrhoeae isolates from 22 European countries (range: 16.5–100%). Multivariable analysis of correlations between resistance and patients’ epidemiological characteristics found tetracycline resistance associated with men who have sex with men (aOR: 1.38; 95% CI: 1.06–1.79). Our results are important when considering measures against transmission of sexually transmitted bacterial infections in Europe, such as in the context of doxycycline post-exposure prophylaxis (doxy-PEP).
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Schröder et al. (2026) studied this question.
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