A selective fluorescent probe for an organophosphorous nerve agent mimic via an oxime-to-isoxazole cascade reaction

Muhammad Shar Jhahan Khan; K. S. Al-Namshah; Muhammad Saleem; Yue Wang

doi:10.1039/d5ra08944a

January 1, 2026RSC AdvancesOpen Access

A selective fluorescent probe for an organophosphorous nerve agent mimic via an oxime-to-isoxazole cascade reaction

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Key Points

The study aims to create a selective fluorescent probe to detect organophosphorous nerve agents.
Utilized a chemical reaction involving oxime and isoxazole
Developed a detection system to identify nerve agents
Implemented analytical techniques to evaluate probe performance
The probe successfully detected organophosphorous mimics
Showed high sensitivity and specificity for the target compounds

Implication

Research develops a fluorescent probe for detecting nerve agents, highlighting the need for effective detection methods.

Abstract

A class of chemical warfare agents and their facile use in terrorist attacks underscores the need to develop accurate system to detect these chemicals.

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Cite This Study

Khan et al. (2026) studied this question.

synapsesocial.com/papers/696c7835eb60fb80d13966fd https://doi.org/10.1039/d5ra08944a

View Full Paper

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A selective fluorescent probe for an organophosphorous nerve agent mimic via an oxime-to-isoxazole cascade reaction

Key Points

Implication

Abstract

Discussion

Cite This Study

A selective fluorescent probe for an organophosphorous nerve agent mimic via an oxime-to-isoxazole cascade reaction

Key Points

Implication

Abstract

Discussion

Cite This Study

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