Abstract Background: Split-thickness skin grafting is the most frequently used procedure in plastic surgery for the replacement of damaged or missing skin. The treatment protocol involves a variety of techniques and dressing materials, and all of them aim for a fast, spontaneous re-epithelialization of the donor sites. Treatment of the split-thickness autograft donor sites has been studied over the years but there is no standard treatment for managing these sites. Recently, chlorhexidine tulle and collagen sheet were found to be effective in the management of donor sites hence, we have undertaken the current study. Methods: This study was prospective in nature on 35 donors operated for Skin grafting in our tertiary care institute. Results: Majority of the cases were from 31-50 years. There were no significant differences in demographic parameters between the two groups at baseline. Collagen dressing had significantly lesser healing time than Chlorhexidine tulle. Incidence of infection was more in CHT group (16.7%). However, the difference was not statistically significant. (p=0.08). Pain score was gradually decreasing in both the groups on subsequent follow up but it was significantly lower in Collagen dressing group at each follow up visit (p< 0.05). Conclusion: Collagen dressing has advantages over chlorhexidine tulle dressing in terms of early re-epithelization and less discomfort during applications.
International Journal of Medical Science and Advanced Clinical Research (IJMACR) (Sun,) studied this question.