Carb Detective: Developing a Compelling Board Game to Learn About the Classification of Monosaccharides

ABSTRACT The development of active learning strategies that position students as the main agents in generating their own knowledge has gained significant momentum in recent years. In particular, serious games have emerged as effective pedagogical tools in chemistry and related subjects. These games actively engage students with the material, increasing their interest and commitment to learning. Herein, we discuss the creation of a pedagogical board game and its implementation in the biochemistry class, as a playful tool for learning carbohydrates specifically monosaccharides. “Carb Detective” was designed to include the essential elements needed to create engaging and enjoyable learning experiences. It was tested with 89 students aged 18–20 years old who were enrolled in general biochemistry courses. The results of this quasi‐experimental educational intervention indicated that the game enabled students to learn several key concepts, including the classification of monosaccharides based on their functional groups, configuration, and the number of carbon atoms. Furthermore, students gained exposure to identify epimers and anomeric carbons, while also studying their stereochemistry, which enhanced their ability to apply these concepts in practical contexts. The findings also suggest that the game promoted competence, motivated students, and improved their understanding of the topic. It provided immediate feedback on “yes” or “no” questions, helping students to correct errors and gain a deeper understanding of the material.