What question did this study set out to answer?

To explore the interactions between cellular senescence, inflammaging, and cardiovascular disease.

January 20, 2026Immunological ReviewsOpen Access

Cellular Senescence, Inflammaging and Cardiovascular Disease

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To explore the interactions between cellular senescence, inflammaging, and cardiovascular disease.
Review of current literature on aging effects in the cardiovascular system
Analysis of cellular senescence and its role in chronic inflammation
Examination of therapeutic strategies targeting aging-related pathways
Cellular senescence contributes to chronic inflammation and cardiovascular dysfunction
Macrophages play a key role in clearing senescent cells
Existing drugs like metformin may offer protective effects against cardiovascular aging

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This review highlights the impact of aging and inflammation on cardiovascular health, suggesting novel therapeutic strategies.

Zanders et al. (2026) studied this question.

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