Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

Yuanhang Yang; Antoine Créon; Andrew S. Levey; Erika Cornu; Aurora Caldinelli; Marie Evans; A. Sjölander; Alberto Ortiz; Edouard L Fu; Andrea Carugno

doi:10.1016/j.kint.2025.11.009

January 16, 2026

Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

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Key Points

The study aims to explore the association between population-based eGFR values and health outcomes related to chronic kidney disease.
Analyzed population-based eGFR values
Established distribution percentiles
Examined associations with kidney failure and mortality rates
eGFR values below the 25th percentile correlate with higher risks of kidney failure
Lower eGFR is associated with increased mortality rates
Population-based eGFR charts can enhance current reporting systems for early identification

Implication

Population-based analysis shows eGFR links to kidney failure and death risks, suggesting prevention opportunities.

Abstract

Our study shows that eGFR values below the 25th percentile of the population distribution are associated with increased risks of kidney failure and death. Population-based eGFR charts may complement current automatic reporting systems and provide opportunities for early identification and primary prevention of CKD.

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/696f1b189e64f732b51ef236 https://doi.org/10.1016/j.kint.2025.11.009

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Ask AI

Bookmark

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Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

Key Points

Implication

Abstract

Discussion

Cite This Study

Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

Key Points

Implication

Abstract

Discussion

Cite This Study

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