Key result
MuRF1 and MAFbx/atrogin-1 expression increases under atrophy-inducing conditions to serve as critical muscle atrophy markers.
Design
Review
Authors
Loading...
MuRF1/MAFbx expression validates atrophy markers in research; leaves open their full roles and therapeutic targeting.
Key points are not available for this paper at this time.
Bodine et al. (2014) studied this question. MuRF1 and MAFbx/atrogin-1 are critical markers of muscle atrophy in skeletal muscle, with increased expression under atrophy-inducing conditions.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: