Pharmacokinetics of the potassium-competitive acid blocker tegoprazan administered by the oral route in healthy Mexicans

Key Points

• The aim is to compare the pharmacokinetics of tegoprazan between Mexicans and Koreans.
• Administered tegoprazan orally to healthy Mexican participants.
• Compared pharmacokinetic data with previously obtained data from Koreans.
• Analyzed the substrate role of tegoprazan in CYP3A4 metabolism.
• No significant pharmacokinetic differences were found between the two populations.
• Efficacy and safety data from Koreans are applicable to Mexicans.