Aptamer-Functionalized 3D Gold Nanodendrite Platform for Electrochemical Detection of Circulating Tumor Cells in Breast Cancer

Key Points

• To develop a platform for electrochemical detection of circulating tumor cells in breast cancer.
• Utilized a 3D gold nanodendrite platform
• Functionalized the platform with specific aptamers
• Conducted electrochemical detection assays for CTCs
• Achieved enhanced sensitivity in detecting CTCs
• Demonstrated potential for distinguishing CTCs from healthy cells
• Showed effectiveness in low abundance scenarios