Disposable Paper-Based Electrochemical Biosensor Employing g-C₃N₄/Carbon Dots and Toll-like Receptor for Ultrasensitive Detection of Gram-Negative Bacteria

Pravat Kumar Sahu; Shuvankar Bhunia; Asha Ramesh; Trinadha Rao Karri; Rahul Gangwar; Nitisha Beniwal; Aravind Kumar Rengan; Siva Rama Krishna Vanjari; Subrahmanyam Challapalli

doi:10.1039/d5tb02535d

January 1, 2026Journal of Materials Chemistry B

Disposable Paper-Based Electrochemical Biosensor Employing g-C₃N₄/Carbon Dots and Toll-like Receptor for Ultrasensitive Detection of Gram-Negative Bacteria

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Key Points

The aim is to develop a cost-effective biosensor for the rapid detection of gram-negative bacteria in water.
Developed a disposable paper-based biosensor using g-C₃N₄ and carbon dots.
Incorporated toll-like receptors for enhanced sensitivity.
Evaluated the performance using water samples to detect bacterial contamination.
Achieved ultrasensitive detection of gram-negative bacteria at low concentrations.
Reduced processing time compared to traditional methods.
Demonstrated potential for on-site and rapid testing.

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Implication

Innovative biosensor detects gram-negative bacteria using g-C₃N₄ and toll-like receptors, indicating a new POC solution.

Abstract

Waterborne bacterial contamination remains a pressing global health concern, demanding point-of-care (POC) devices for rapid and efficient on-site detection. High costs, long processing times and reliance on sophisticated equipment limit...

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Sahu et al. (2026) studied this question.

synapsesocial.com/papers/69706d13b6488063ad5c1e17 https://doi.org/10.1039/d5tb02535d

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Disposable Paper-Based Electrochemical Biosensor Employing g-C₃N₄/Carbon Dots and Toll-like Receptor for Ultrasensitive Detection of Gram-Negative Bacteria

Key Points

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Implication

Abstract

Discussion

Cite This Study

Disposable Paper-Based Electrochemical Biosensor Employing g-C₃N₄/Carbon Dots and Toll-like Receptor for Ultrasensitive Detection of Gram-Negative Bacteria

Key Points

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Implication

Abstract

Discussion

Cite This Study

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