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January 22, 2026Proceedings of the National Academy of Sciences0 citations

Scaling the glassy dynamics of active particles: Tunable fragility and reentrance

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PPPuneet PareekPSPeter SollichSNSaroj Kumar Nandi

Key Points

  • This research aims to understand how self-propulsion affects the glassy dynamics of active particles in dense systems.
  • Simulated a model system of active particles and biological tissues.
  • Varied self-propulsion forces and persistence time.
  • Analyzed the phase diagram with fluid and glass phases.
  • Identified nonmonotonic relaxation time evolution based on persistence time.
  • Described crossover from glassy to jamming behavior.
  • Observed tunable glass fragility similar to passive systems.

Abstract

Understanding the influence of activity on dense amorphous assemblies is crucial for biological processes such as wound healing, embryogenesis, or cancer progression. Here, we study the effect of self-propulsion forces of amplitude f 0 and persistence time τ p in dense assemblies of soft repulsive particles by simulating a model particle system that interpolates between particulate active matter and biological tissues. We identify the fluid and glass phases of the three-dimensional phase diagram obtained by varying f 0 , τ p , and the packing fraction ϕ . The morphology of the phase diagram accounts for a nonmonotonic evolution of the relaxation time with τ p , which is a direct consequence of the crossover in the dominant relaxation mechanism, from glassy to jamming. A second major consequence is the evolution of the glassy dynamics from sub-Arrhenius to super-Arrhenius. We show that this tunable glass fragility extends to active systems analogous observations reported for passive particles. This analogy allows us to apply a dynamic scaling analysis proposed for the passive case, in order to account for our results for active systems. Finally, we discuss similarities and differences between our results and recent findings in the context of computational models of biological tissues.

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Cite This Study

Pareek et al. (2026) studied this question.

synapsesocial.com/papers/6971bd6a642b1836717e209dhttps://doi.org/10.1073/pnas.2516624123
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