Case reports reveal significant improvement with anti-TB therapy in children with anterior chest wall swelling, suggesting careful evaluation for tuberculosis.
Tuberculosis (TB) is one of the most common infectious diseases in India with paediatric TB accounting for approximately 6-7% of cases. Skeletal and soft tissue are rare sites for TB. Three cases seen in a western tertiary hospital in India aged between 1 and 11 years presented with a swelling on the anterior chest wall. None had any known TB contact. Imaging demonstrated the presence of collections and underlying bony as well as pulmonary/pleural involvement. All were positive for TB on histopathology. They were commenced on anti-TB therapy and there was significant improvement on follow-up. Hence, tuberculosis with intrathoracic extension must be borne in mind as a close differential diagnosis when evaluating anterior chest wall swelling as it is treatable, especially in endemic areas.
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Saoji et al. (2026) studied this question.
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