What question did this study set out to answer?

The study aims to evaluate clinical outcomes of endolymphatic sac surgery and identify preoperative factors affecting success in Ménière’s disease.

January 22, 2026Audiology ResearchOpen Access

Endolymphatic Sac Surgery in Refractory Ménière’s Disease: Exploratory Associations and Postoperative Clinical Outcomes in a Bicentric Cohort

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Authors

ELEleonore LebelleAix-Marseille Université MTMaria-Pia TusetFondation Ophtalmologique Adolphe de Rothschild RHRalph HaddadCentre National de la Recherche Scientifique

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Implication

This exploratory cohort study examines surgical outcomes of endolymphatic sac surgery for refractive Ménière’s disease, indicating potential predictors of success.

Key Points

The study aims to evaluate clinical outcomes of endolymphatic sac surgery and identify preoperative factors affecting success in Ménière’s disease.
Retrospective bicentric cohort study with 45 patients undergoing endolymphatic sac surgery.
Assessment of vertigo control using AAO-HNS criteria and hearing outcomes through audiometry.
Univariate analyses to explore associations between various factors and treatment outcomes.
Surgical success (Class A/B vertigo control) achieved in 66.7% of patients.
Longer disease duration (>5 years) linked to better outcomes (87.5% success) compared to shorter duration (55.2%).
Hearing preservation rate declined from 77.5% at 45 days to 50% at 2 years post-surgery.
Seven patients experienced Tumarkin attacks, with five requiring further intervention.
Low morbidity with one significant complication (labyrinthitis).

Cite This Study

Lebelle et al. (2026) studied this question.

synapsesocial.com/papers/6971bdec642b1836717e2917 https://doi.org/10.3390/audiolres16010015

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Implication

This exploratory cohort study examines surgical outcomes of endolymphatic sac surgery for refractive Ménière’s disease, indicating potential predictors of success.

Endolymphatic Sac Surgery in Refractory Ménière’s Disease: Exploratory Associations and Postoperative Clinical Outcomes in a Bicentric Cohort

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Implication

Key Points

Cite This Study

Endolymphatic Sac Surgery in Refractory Ménière’s Disease: Exploratory Associations and Postoperative Clinical Outcomes in a Bicentric Cohort

Discussion

Member takes

Implication

Key Points

Cite This Study

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