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The aim is to evaluate growth and clinical outcomes in a patient with Mauriac syndrome after treatment with automated insulin delivery.

January 22, 2026JCEM Case ReportsOpen Access

Mauriac Syndrome: Growth and Clinical Outcomes After 2.5 Years of Automated Insulin Delivery Treatment

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The aim is to evaluate growth and clinical outcomes in a patient with Mauriac syndrome after treatment with automated insulin delivery.
Case report of a 14-year-old male with type 1 diabetes and Mauriac syndrome.
Initial management included multiple daily insulin injections and growth hormone therapy.
Transitioned to automated insulin delivery after identification of hepatomegaly.
Automated insulin delivery resulted in decreased hemoglobin A1c levels.
Normal liver enzyme levels and resolution of hepatomegaly were observed.
Significant progression of puberty and growth aligned with mid-parental height.

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Case report illustrates improved growth and liver function in a young male with Mauriac syndrome using automated insulin delivery.

AlArab et al. (2025) studied this question.

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