The research aims to synthesize and evaluate triazole derivatives as potential anticancer agents.
Synthesis of triazole derivatives through Cu(i)-catalyzed click chemistry.
Structural characterization of the synthesized compounds.
Molecular docking analysis to assess binding affinity to cancer targets.
A series of novel triazole derivatives was successfully synthesized.
Structural characterization confirmed the expected configuration of the derivatives.
Initial evaluations suggest promising anticancer activity for the synthesized compounds.
Abstract
A series of novel ( p -tolylthio)methyl-linked 1,2,3-triazole derivatives 10–17 was synthesized via Cu( i )-catalyzed click chemistry and structurally characterized.