Epidemiology and outcome of intra-abdominal infections in intensive care unit in Italy from the Italian Register of complicated Intra-abdominal InfectionS—the IRIS study: a prospective observational nationwide study

Key Points

• To investigate the epidemiology and outcomes of intra-abdominal infections in ICU patients and identify factors leading to mortality.
• Conducted a nationwide observational study across ICUs in Italy.
• Analyzed data from the Italian Register of complicated Intra-abdominal Infections (IRIS).
• Evaluated patient risk factors associated with in-hospital mortality.
• Septic shock is the leading cause of ICU admissions for intra-abdominal infections.
• Immunosuppression and serious comorbidities significantly increase the risk of mortality.
• Modifiable factors such as timely intervention and effective source control can improve patient outcomes.