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January 22, 2026Chemical Communications2 citations

Oxetanes in Heterocycle Synthesis: Recent Advances

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SLShuxuan LiuGLGonghan LiuYWYuquan Wang

Key Points

  • The review aims to compile and discuss recent advancements in the use of oxetanes for synthesizing heterocycles.
  • Summarizes literature from 2019 to 2025
  • Highlights reaction mechanisms and methodologies involving oxetanes
  • Analyzes the regioselectivity and ring strain associated with oxetanes
  • Oxetanes demonstrate high regioselectivity in reactions
  • Recent methods showcase their effectiveness as building blocks in heterocycle formation
  • Advancements indicate a growing interest in oxetanes in synthetic chemistry

Abstract

Owing to their balanced ring strain and the high regioselectivity of their reactions, oxetanes have emerged as versatile building blocks for heterocycle synthesis. This review summarizes representative advances (2019-2025) in...

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6971be8d642b1836717e3305https://doi.org/10.1039/d5cc06673e
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