Systematic review reveals challenges in diagnosing IgG4-related prostatitis, suggesting the need for further studies.
IgG4-related prostatitis is a rare and likely under-recognised manifestation of IgG4-RD. Its overlap with benign and malignant prostatic disorders delays diagnosis. Serum IgG4 and PSA are unreliable markers of disease and monitoring. Glucocorticoids remain first-line therapy, with surgery in obstructive cases. Multicentre studies are needed to define prevalence, natural history, and optimal management.
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Pamfil et al. (2025) studied this question.
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