Impact of Artificial Intelligence for Detection of Precancerous Colonic Lesions in a Fecal Immunochemical Blood Test-Based Organized Screening Program in Italy: A Randomized Control Trial.

Key Points

To determine the effectiveness of artificial intelligence in detecting precancerous colonic lesions within a fecal immunochemical test-based screening program.
Conducted a randomized control trial in Italy.
Utilized artificial intelligence algorithms for lesion detection.
Implemented a fecal immunochemical test-based screening program.
AI did not significantly enhance detection of advanced adenoma detection rate (AADR).

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Randomized control trial evaluates AI's effect on colonic lesion detection in Italy, suggesting limited benefits.

In a FIT-based organized CRC screening setting, CADe did not enhance detection of AADR with a modest increase in withdrawal time. NCT04441580.

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Luca et al. (2026) studied this question.

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