What question did this study set out to answer?

To investigate the prevalence and molecular epidemiology of respiratory adenovirus in children in Shenzhen, China.

January 23, 2026Scientific ReportsOpen Access

The changed endemic pattern of human adenovirus from species C to B among children in 2022–2024 in Shenzhen, China

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This observational study assesses adenovirus patterns in children, revealing a shift from type C to B, suggesting changing infection dynamics.

To investigate the prevalence and molecular epidemiology of respiratory adenovirus in children in Shenzhen, China.
Enrolled children under 14 years from hospitals and communities in Shenzhen between 2022 and 2024.
Collected respiratory specimens for adenovirus testing.
Compared positive rates using Pearson’s chi-square test and performed phylogenetic analysis on virus strains.
The positivity rate for adenovirus among hospitalized children was 16.7%, predominantly HAdV-B3.
The rate increased significantly from 3.4% the previous year, when HAdV-C1 was predominant.
Higher adenovirus positivity was found in hospitalized children compared to outpatient children.
Boys had a lower positive rate than girls in community settings.

Niu et al. (2026) studied this question.

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This observational study assesses adenovirus patterns in children, revealing a shift from type C to B, suggesting changing infection dynamics.