What question did this study set out to answer?

This research aims to evaluate the effects of a supervised exercise program on fatigue and quality of life in patients with quiescent inflammatory bowel disease.

January 23, 2026Journal of Crohn s and Colitis

P0863The effect of intensive physical exercise on fatigue and quality of life in patients with quiescent inflammatory bowel disease: a multicentre randomised controlled trial (ENERGIZE-IBD trial)

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Authors

JHJan C.M. HendriksRijnstate Hospital DODorien OomkensRadboud University Nijmegen JBJ Van BerloRijnstate Hospital

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Implication

Multicentre trial shows exercise reduces fatigue and enhances quality of life in IBD patients, indicating exercise as a potential remedy.

Key Points

This research aims to evaluate the effects of a supervised exercise program on fatigue and quality of life in patients with quiescent inflammatory bowel disease.
Conducted a multicentre, randomised controlled trial.
Included adults aged 18-67 with quiescent IBD and chronic fatigue.
Intervention involved a 12-week exercise program with aerobic and resistance training.
Participants underwent cardiopulmonary exercise testing before and after the intervention.
Fatigue significantly decreased in the exercise group compared to control (p = 0.014).
Quality of life improved in the exercise group (p = 0.024).
Anxiety symptoms reduced significantly in the exercise group (p = 0.02).
Cardiorespiratory fitness measures improved in the exercise group (p < 0.001 for VO2max).
No significant changes in depressive symptoms or sleep quality between groups.

Cite This Study

Hendriks et al. (2026) studied this question.

synapsesocial.com/papers/69730ef2c8125b09b0d1ed0d https://doi.org/10.1093/ecco-jcc/jjaf231.1044

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P0863The effect of intensive physical exercise on fatigue and quality of life in patients with quiescent inflammatory bowel disease: a multicentre randomised controlled trial (ENERGIZE-IBD trial)

Discussion

Member takes

Implication

Key Points

Cite This Study

P0863The effect of intensive physical exercise on fatigue and quality of life in patients with quiescent inflammatory bowel disease: a multicentre randomised controlled trial (ENERGIZE-IBD trial)

Discussion

Member takes

Implication

Key Points

Cite This Study

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