ANCA-associated vasculitis in the United Arab Emirates: a 17-year case series with review from Gulf literature

January 1, 2026Annals of Saudi MedicineOpen Access

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Key Points

The study aims to investigate the frequency, clinical features, and management of ANCA-associated vasculitis in the UAE over 17 years.
Retrospective observational case series design
Analysis of patients diagnosed with GPA, MPA, or EGPA from 2008 to 2024
Data collection included demographic, clinical, laboratory, and treatment information
ANCA testing performed using enzyme-linked immunosorbent assays
Descriptive statistical analysis to summarize findings
Identified 26 AAV patients with a median age of 52.5 years
Microscopic polyangiitis was the most common subtype (50%)
Almost all cases tested positive for ANCA
Overall relapse rate was 31%, and mortality rate was 19%
Noted a need for multicenter studies to better understand AAV in the region.

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Observational study explores the clinical characteristics of ANCA-associated vasculitis in the UAE, indicating significant gaps in understanding.

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Shahrour et al. (2026) studied this question.

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