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January 23, 2026JAMA Dermatology5 citations

Risk of Acne With JAK Inhibitors Versus Th2 Cytokine Inhibitors in Atopic Dermatitis

Risk of Acne in Patients With Atopic Dermatitis Starting a JAK Inhibitor vs Th2 Cytokine Inhibitor

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Authors

MSMaria C. SchneeweissRWRichard WyssPAPriyanka Anand

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Overview

Cohort study evaluates acne risk in patients with atopic dermatitis starting JAK inhibitors, indicating treatment implications.

Key Points

  • The study aims to evaluate the risk of developing acne in patients with atopic dermatitis receiving JAK inhibitors compared to Th2 cytokine inhibitors.
  • Cohort study design
  • Patient population includes adults with atopic dermatitis
  • Comparison of acne incidence between JAK and Th2 cytokine inhibitors
  • Increased risk of acne observed in patients on JAK inhibitors compared to those on Th2 cytokine inhibitors
  • Specific quantitative data not provided, but significant differences noted

Cite This Study

Schneeweiss et al. (2026) studied this question.

synapsesocial.com/papers/69730f59c8125b09b0d1f17bhttps://doi.org/10.1001/jamadermatol.2025.5443
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