What question did this study set out to answer?

January 23, 2026Journal of Crohn s and Colitis

P0756Real-world efficacy and safety of upadacitinib for moderate-to-severe Inflammatory Bowel Disease: A prospective cohort study from China

View Full Paper

Ask AI

Bookmark

This study aims to evaluate the real-world efficacy and safety of upadacitinib in Chinese patients with moderate-to-severe inflammatory bowel disease.
Single-center, prospective cohort design.
Patients with moderate-to-severe Crohn's disease and ulcerative colitis were enrolled.
Data on treatment efficacy and adverse events were collected across a treatment period.
Assessment of clinical and endoscopic remission rates.
Multivariate analysis was performed to identify factors influencing remission.
70.3% clinical remission at week 12, 68.2% at week 52 for Crohn's disease.
Clinical remission for ulcerative colitis increased from 55.3% at week 12 to 90.0% at week 52.
Endoscopic remission observed in 66.7% of UC patients at week 52.
35.0% of patients experienced adverse events, with 17.2% classified as severe.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Prospective cohort study reports high efficacy and safety of upadacitinib in Chinese patients with inflammatory bowel disease, suggesting its therapeutic potential.

Cite This Study

Yao et al. (2026) studied this question.

synapsesocial.com/papers/69731047c8125b09b0d1ff20 https://doi.org/10.1093/ecco-jcc/jjaf231.937

View Full Paper

Ask AI

Bookmark

Implication

Prospective cohort study reports high efficacy and safety of upadacitinib in Chinese patients with inflammatory bowel disease, suggesting its therapeutic potential.

P0756Real-world efficacy and safety of upadacitinib for moderate-to-severe Inflammatory Bowel Disease: A prospective cohort study from China

Key Points

Discussion

Implication

Cite This Study

P0756Real-world efficacy and safety of upadacitinib for moderate-to-severe Inflammatory Bowel Disease: A prospective cohort study from China

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider