Demonstrates effective carbon–carbon bond formation in carbonyl compounds, suggesting practical applications for organic synthesis.
Photocatalytic reductive radical‐polar crossover is a versatile platform for achieving carbon–carbon bond formations under mild conditions and is complementary to traditional radical reactivity. Herein, we report a study on the reactivity of esters and ketones under this platform to produce cyclic ketone and alcohol products, respectively. The process is amenable to a variety of functionalized systems, and mechanistic experiments suggest intermediacy of both a benzylic radical and anion arising from photocatalytic reduction.
No takes yet. Share an insight, caveat, or question.
Pillon et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: